Gap junction-mediated intercellular communication in ischemic preconditioning
نویسندگان
چکیده
منابع مشابه
Gap junction-mediated intercellular communication in ischemic preconditioning.
Gap junction-mediated communication can modulate cell death in different tissues. In myocardium, gap junction communication is altered during ischemia, which contributes to the development of arrhythmias, but still allows synchronization of the onset of rigor contracture in the progression of injury. During reperfusion, gap junction communication allows cell-to-cell spread of hypercontracture a...
متن کاملGap junction-mediated intercellular communication in the immune system.
Immune cells are usually considered non-attached blood cells, which would exclude the formation of gap junctions. This is a misconception since many immune cells express connexin 43 (Cx43) and other connexins and are often residing in tissue. The role of gap junctions is largely ignored by immunologists as is the immune system in the field of gap junction research. Here, the current knowledge o...
متن کاملRegulation of hematopoiesis by gap junction-mediated intercellular communication.
Gap junctions are intercellular channels formed by individual structural units known as connexins (Cx) that allow the intercellular exchange of small molecules between cells. The presence of Cx protein in bone marrow and thymic stromal cells and the demonstration that these cells are functionally coupled have led to the hypothesis that groups of stromal cells in the bone marrow and thymus form ...
متن کاملAssembly of gap junction intercellular communication channels.
788 with a lipidlprotein molar ratio of 100:1, a value close to that found in most biological membranes [21]. The data show that the calculation of distances between sites within the monomer of a membrane protein of a cross-sectional diameter of 5 nm based only from FET efficiency measurements is largely speculative in most cases in native biological membranes. Because the contribution of FET t...
متن کاملGap junction mediated miRNA intercellular transfer and gene regulation: A novel mechanism for intercellular genetic communication.
Intercellular genetic communication is an essential requirement for coordination of cell proliferation and differentiation and has an important role in many cellular processes. Gap junction channels possess large pore allowing passage of ions and small molecules between cells. MicroRNAs (miRNAs) are small regulatory RNAs that can regulate gene expression broadly. Here, we report that miRNAs can...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2002
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(02)00441-8